WoS (Web of Science) İndeksli Yayınlar

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Browsing WoS (Web of Science) İndeksli Yayınlar by Title

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    1,15-diaza-3,4:12,13-dibenzo-5,8,11-trioxacycloheptadecane hemihydrate
    (2003) Bilge, Selen; Kılıç, Zeynel; Fen Fakültesi
    The title compound, C20H26N2O 3·0.5H2O, contains a 17-membered diaza-crown ether ligand with three ether O and two N atoms. It consists of the macrocyclic ligand and one half water molecule; the latter possesses crystallographically imposed C2 symmetry. In the macrocyclic ring, the mean N⋯O distance is 3.995 (4) A. The macrocyclic inner hole size, estimated as twice the mean distance of the donor atoms from their centroid, is approximately 1.29 Å. © 2003 International Union of Crystallography Printed in Great Britain - all rights reserved.
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    1-n-Butyl-2-(4′-fluorophenyl)-1H-benzimidazole-6-carbonitrile
    (2004) Göker, Hakan; Kuş, Canan; Eczacılık Fakültesi
    The structure of the title compound, C18H16FN3, consists of neutral mol­ecules. The asymmetric unit contains two independent mol­ecules with similar conformations: the dihedral angles between the benz­imidazole moiety and the benzene rings are 34.99 (9) and 36.08 (8)°. The crystal structure is stabilized by dipole-dipole and van der Waals interactions.
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    16+ spin-gap isomer in Cd96
    (2011) Ataç, Ayşe; Fen Fakültesi
    A β-decaying high-spin isomer in Cd96, with a half-life T 1/2=0.29-0.10+0.11s, has been established in a stopped beam rare isotope spectroscopic investigations at GSI (RISING) experiment. The nuclei were produced using the fragmentation of a primary beam of Xe124 on a Be9 target. From the half-life and the observed γ decays in the daughter nucleus, Ag96, we conclude that the β-decaying state is the long predicted 16 + "spin-gap" isomer. Shell-model calculations, using the Gross-Frenkel interaction and the πν(p1/2,g9/2) model space, show that the isoscalar component of the neutron-proton interaction is essential to explain the origin of the isomer. Core excitations across the N=Z=50 gaps and the Gamow-Teller strength, B(GT) distributions have been studied via large-scale shell-model calculations using the πν(g,d,s) model space to compare with the experimental B(GT) value obtained from the half-life of the isomer. © 2011 American Physical Society.
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    2,2′-[1,1′-(Propane-2,2-diyldiimino)-diethyl-idene]-diphenol
    (2007) Atakol, Orhan; Kenar, Adnan; Fen Fakültesi
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    2,6-Dimethyl-4H-1-benzopyran-4-one
    (2004) Göker, Hakan; Eczacılık Fakültesi
    The title compound, C11H10O2, belongs to the class of 4-benzopyrones (also known as chromen-4-ones) with potentially diverse pharmacological activities. It was synthesized by acyl­ation of 2-hydroxy-4-methyl­aceto­phenone with ethyl acetate in the presence of sodium hydride and subsequent cyclization by hydro­chloric acid. All non-H atoms of the substituted bicyclic mol­ecule are coplanar within 0.03 Å. C-H...O interactions [C...O = 3.272 (5) Å] link neighbouring mol­ecules related by the 21 axis
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    2-Acetyl­phenyl 5-methyl­thio­phene-2-carboxyl­ate
    (2003) Göker, Hakan; Fen Fakültesi
    The non-H atoms of the molecule of the title compound, C14H 12O3S, form three essentially planar fragments, viz. the thiophene ring with the methyl C atom and carboxylate group (maximum deviation 0.041 Å; fragment A), the oxyphenyl ring with the central acetyl C atom (0.029 Å; B), and the acetyl group together with the phenyl C atom bonded to it (<0.001 Å; C). These planes form dihedral angles of 88.33 (7)° for A/B and 71.9 (2)° for B/C. The crystal structure is stabilized by intermolecular interactions of the C - H⋯O type [C⋯O = 3.492 (5) Å]. © 2003 International Union of Crystallography Printed in Great Britain - all rights reserved.
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    3-(4-Chlorobenzyl)-5-(4-oxo-4H-chromen-3-ylmethylene)-1,3-thiazolidine-2,4-dione
    (2005) Bozdağ Dündar, Oya; Ertan, Rahmiye; Ünlüsoy, Meltem Ceylan; Eczacılık Fakültesi
    In the title mol­ecule, C20H12ClNO4S, the benzopyran ring system and the thia­zolidine ring are planar. The dihedral angle between the chloro­benzyl and thia­zolidine rings is 74.42 (8)°. The crystal structure is stabilized by intermolecular C-H...O hydrogen bonds.
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    3-Ethyl-5-(4-oxochroman-3-ylmethylene)- 1,3-imidazolidine-2,4-dione
    (2007) Ünlüsoy, Meltem Ceylan; Ertan, Rahmiye; Eczacılık Fakültesi
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    3-Methyl-5-(4-oxo-4H-chromen-3-ylmethylene)-1,3-thiazolidine-2,4-dione
    (2006) Ünlüsoy, Meltem Ceylan; Ertan, Rahmiye; Eczacılık Fakültesi
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    4,4,6,6-Tetrachloro-1′,3′-[2,2′-(3-oxapentane-1,5-dioxy) dibenzyl]-2λ5,4λ5,6λ5- cyclotriphosphazene-2-spiro-2′-1,3,2-diazaphospholane benzene hemisolvate
    (2004) Bilge, Selen; Demiriz, Şemsay; Kılıç, Zeynel; Fen Fakültesi
    . Read articleSimilar articles Supporting information cif Crystallographic Information File (CIF) https://doi.org/10.1107/S1600536804017118/wn6263sup1.cif Contains datablocks I, global hkl Structure factor file (CIF format) https://doi.org/10.1107/S1600536804017118/wn6263Isup2.hkl Contains datablock I CCDC reference: 248827 checkCIF report Supplementary crystallographic information 3D view Supporting crystallographic data
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    4,4,6,6-Tetrachloro-4a0,80-dihydrodinaphtho- [2,1-c0;2,1-g0]-2k5 ,4k5 ,6k5 -cyclotriphosphazene1-spiro-10-[2,5,8a,1]dioxazaphosphanaphthalene
    (2004) İlter, Elif Ece; Kılıç, Zeynel; Fen Fakültesi
    The title compound, C22H15Cl4N4O2P3, is a spiro phosphazene derivative with two bulky naphthalene rings. The phosphazene and the two six-membered N/O rings are not planar. The aliphatic C atom (in ArCH-OAr) and the N atom (in ArCH2-N), which has a pyramidal geometry, are capable of representing stereogenic centres.
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    4-Thiazolidinone Derivatives as MMP Inhibitors in Tissue Damage: Synthesis, Biological Evaluation and Docking Studies
    (2018) Yalçın, İsmail; Ertan-Bolelli, Tuğba; Eczacılık Fakültesi
    Nine 2-(1,2-benzothiazol-3-yl)-N-(4-oxo-2-phenyl-1,3-thiazolidin-3-yl)propanamides combining a benzisothiazole and 4-thiazolidinone in one framework were designed and synthesized. The aim of the study was to verify their effectiveness to affect the inflammatory/oxidative process in which free oxygen and nitrite (ROS and RNS) radicals, inflammatory mediators, such as nuclear factor κB (NF-κB), and matrix metalloproteinases (MMPs) are involved. Docking studies of all the compounds were performed in order to explore their binding mode at the MMP-9 protein. An appreciable anti-inflammatory/potential wound healing effects of the tested compounds was highlighted. Derivative 23, bearing a 4-carboxyphenyl substituent at C2 of the 4-thiazolidinone ring, exhibited the highest activity, being able to inhibit MMP-9 at nanomolar level(IC50 = 40 nM). © 2018 by the authors.
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    4-Thiazolidinone derivatives as mmp ınhibitors in tissue damage: synthesis, biological evaluation and docking studies
    (2018) Yalçın, İsmail; Ertan, Tuğba Bolelli; Eczacılık Fakültesi
    Nine 2-(1,2-benzothiazol-3-yl)-N-(4-oxo-2-phenyl-1,3-thiazolidin-3-yl)propanamides combining a benzisothiazole and 4-thiazolidinone in one framework were designed and synthesized. The aim of the study was to verify their effectiveness to affect the inflammatory/oxidative process in which free oxygen and nitrite (ROS and RNS) radicals, inflammatory mediators, such as nuclear factor kappa B (NF-kappa B), and matrix metalloproteinases (MMPs) are involved. Docking studies of all the compounds were performed in order to explore their binding mode at the MMP-9 protein. An appreciable anti-inflammatory/potential wound healing effects of the tested compounds was highlighted. Derivative 23, bearing a 4-carboxyphenyl substituent at C2 of the 4-thiazolidinone ring, exhibited the highest activity, being able to inhibit MMP-9 at nanomolar level(IC50 = 40 nM).
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    60,60-Dichloro-3,300-etheno-3,4,300,400- tetrahydro-2H-1,3-benzoxazine-2-spiro20-(2k5 ,4k5 ,6k5 -cyclotriphosphazene)-40 - spiro-200-2H-1,3-benzoxazine
    (2004) Bilge, Selen; Natsagdorj, Amgalan; Demiriz, Şemsay; Kılıç, Zeynel; Fen Fakültesi
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    7,11-(Butane-1,4-diyldioxydi-o-phenylenedimethylene)-6,6-dichloro-4,4-bis(pyrrolidin1-yl)-2k5 ,4k5 ,6k5 -triphosphaza-1,3,5,7,11- pentaazaspiro[5.5]undeca-1,3,5-triene
    (2005) Asmafiliz, Nuran; İlter, Elif Ece; Kılıç, Zeynel; Fen Fakültesi
    The title compound, C29H42Cl2N7O2P3, is a phosphazene derivative with a bulky substituent attached through a spiro junction with two pyrrolidine rings. The six-membered C3N2P ring has a chair conformation, while the phosphazene ring has a slight envelope conformation. The two N atoms in the C3N2P ring are likely to be stereogenic.
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    A linear homotrinuclear nickel(II) complex with a reduced ONNO-type Schiff base
    (2005) Yüzer, Devrim; Atakol, Orhan; Fen Fakültesi
    The structure of the title compound, [mu]-formato-bis­{[mu]-N,N'-bis[1-(2-oxidophen­yl)eth­yl]-2-hydr­oxy-1,3-propane­diamine}bis­[(N,N-di­methyl­form­amide)nickel(II)] N,N-di­methyl­form­am­ide disolvate, [Ni3(CHO2)2(C19H24N2O3)2(C3H7NO)2]·2C3H7NO, comprises a centrosymmetric linear homotrinuclear nickel(II) complex. The central and terminal nickel(II) atoms have distorted octa­hedral coordination geometries.
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    A measurement of the calorimeter response to single hadrons and determination of the jet energy scale uncertainty using LHC Run-1 pp-collision data with the ATLAS detector
    (2017) Çakır, Orhan; Yıldız, Hatice Duran; Çiftçi, Abbas Kenan; Fen Fakültesi
    A measurement of the calorimeter response to isolated charged hadrons in the ATLAS detector at the LHC is presented. This measurement is performed with 3.2 nb- 1 of proton–proton collision data at s=7 TeV from 2010 and 0.1 nb- 1 of data at s=8 TeV from 2012. A number of aspects of the calorimeter response to isolated hadrons are explored. After accounting for energy deposited by neutral particles, there is a 5% discrepancy in the modelling, using various sets of Geant4 hadronic physics models, of the calorimeter response to isolated charged hadrons in the central calorimeter region. The description of the response to anti-protons at low momenta is found to be improved with respect to previous analyses. The electromagnetic and hadronic calorimeters are also examined separately, and the detector simulation is found to describe the response in the hadronic calorimeter well. The jet energy scale uncertainty and correlations in scale between jets of different momenta and pseudorapidity are derived based on these studies. The uncertainty is 2–5% for jets with transverse momenta above 2 TeV, where this method provides the jet energy scale uncertainty for ATLAS. © 2017, CERN for the benefit of the ATLAS collaboration.
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    A measurement of the calorimeter response to single hadrons and determination of the jet energy scale uncertainty using LHC Run-1 pp-collision data with the ATLAS detector
    (2017) Çakır, Orhan; Yıldız, Hatice Duran; Fen Fakültesi; Hızlandırıcı Teknolojileri Enstitüsü
    A measurement of the calorimeter response to isolated charged hadrons in the ATLAS detector at the LHC is presented. This measurement is performed with 3.2 nb(-1) of proton-proton collision data at root s = 7 TeV from 2010 and 0.1 nb(-1) of data at root s = 8 TeV from 2012. A number of aspects of the calorimeter response to isolated hadrons are explored. After accounting for energy deposited by neutral particles, there is a 5% discrepancy in the modelling, using various sets of GEANT4 hadronic physics models, of the calorimeter response to isolated charged hadrons in the central calorimeter region. The description of the response to anti-protons at low momenta is found to be improved with respect to previous analyses. The electromagnetic and hadronic calorimeters are also examined separately, and the detector simulation is found to describe the response in the hadronic calorimeter well. The jet energy scale uncertainty and correlations in scale between jets of different momenta and pseudorapidity are derived based on these studies. The uncertainty is 2-5% for jets with transverse momenta above 2 TeV, where this method provides the jet energy scale uncertainty for ATLAS.